Treatment of Stage II Non-Small Cell Lung Cancer

For information about the treatments listed below, see the Treatment Option Overview section.

Treatment of stage IIA non-small cell lung cancer and stage IIB non-small cell lung cancer may include the following:

• Surgery (wedge resection, segmental resection, sleeve resection, lobectomy, or pneumonectomy).
• Surgery followed by chemotherapy.
• Surgery followed by targeted therapy with an EGFR tyrosine kinase inhibitor, such as osimertinib.
• Surgery followed by immunotherapy, such as atezolizumab.
• Surgery followed by radiation therapy.
• Chemotherapy followed by surgery.
• Immunotherapy, such as nivolumab, and chemotherapy followed by surgery.
• External radiation therapy for patients who cannot have surgery.
• A clinical trial of radiation therapy following surgery.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.